Topiramate (Topamax): Evolving Role in Weight Reduction …
网页2023年8月31日 · The baseline weight was reduced by 82% at three months and 86% at one year. The mean body weight was reduced by 3.9% of the baseline at three months and 7.3% of the baseline at one year. In patients with a BMI > 30, the mean weight loss was 4.3% at three months and 10.9 kg at one year.
Topamax (Topiramate) for Weight Loss - Verywell Health
网页2024年2月26日 · Weight loss as a percentage of baseline body weight ranged from a 4.8% to a 9.7% decrease in multiple clinical trials that included Topamax. Therefore, it may be a good option for many people trying to lose weight as a drug treatment option along with dietary and exercise lifestyle interventions.
Topamax for Weight Loss: Side Effects, Dosages, and Tips - GoodRx
网页2024年3月13日 · Studies show that on average, people taking Topamax lose around 11 lbs. Higher doses and longer duration of use generally result in more weight loss. The most common side effects associated with Topamax for weight loss are abnormal skin sensations (like burning, tingling, numbness), altered sense of taste, and slowed thinking and movements.
Efficacy and safety of topiramate on weight loss: a meta-analysis …
网页The results of meta-regression analyses found that the effect of topiramate on weight loss increased with treatment duration and dosage. Participants with diabetes who were treated with topiramate lost a mean of 5.25 kg (95% CI -6.66 to -3.85 kg; four trials) of additional weight compared with placebo-treated participants, but substantial ...
Does topiramate cause weight loss? - Drugs.com
网页2024年1月19日 · Yes, topiramate (Topamax) has been shown to cause weight loss when used for both seizure control and migraine prevention. Anorexia (loss of appetite), which may contribute to weight loss, has also been reported in studies in both children and adults, although no correlation was made in studies.
Efficacy and safety of topiramate on weight loss: a meta‐analysis …
网页2011年4月27日 · Patients treated with topiramate lost an average of 5.34 kg (95% confidence interval [95%CI]−6.12 to −4.56) of additional weight as compared with placebo. According to meta-regression analysis, treatment duration and dosage were associated with the efficacy of topiramate treatment.
Clinical effectiveness and predictors of response to topiramate …
网页2024年5月10日 · As lifestyle modification therapy alone often fails to result in clinically significant and durable weight loss (e.g., Danielsson et al. showed that 2% of adolescents with severe obesity [BMI ≥ 1.2 times the 95th percentile] receiving 3 years of lifestyle modification experienced significant weight loss) ( 2 ), …
Topamax for Weight Loss: Pros & Cons - Buzzrx
网页2023年11月30日 · Clinical trials show that using Topamax for weight loss can achieve about 5.34 kilograms (kg), which is about 11.7 pounds (lbs). You may start to notice some weight loss after about 4 weeks. Topamax is an anticonvulsant medication that is used to manage seizures. Certain brands of Topamax are also used for migraine prevention.
Efficacy and safety of topiramate on weight loss: a meta ... - PubMed
网页Patients treated with topiramate lost an average of 5.34 kg (95% confidence interval [95%CI]-6.12 to -4.56) of additional weight as compared with placebo. According to meta-regression analysis, treatment duration and dosage were associated with the efficacy of topiramate treatment.
Topiramate (Topamax): Evolving Role in Weight Reduction
网页2023年8月31日 · Notably, topiramate may contribute to weight loss by reducing calorie intake, decreasing fat gain, and lowering triglyceride and cholesterol levels. Additionally, its impact on reward pathways associated with food could play a role. Multiple clinical studies have supported the use of topiramate as a weight-loss medication.
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