The Anti-Cancer Mechanisms of Berberine: A Review
网页2020年1月30日 · Therefore, development of strategies to prevent and treat cancer is critical. 1 Berberine (BBR), a small molecule isoquinoline alkaloid extracted from the rhizomes of coptis chinensis and hydrastis canadensis, is traditionally used to treat bacterial diarrhea. 2 Recent studies showed that BBR reduced lipid levels and glycemic index, and exerted ...
Berberine as a Potential Anticancer Agent: A Comprehensive …
网页2021年12月4日 · Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial amount of research has been conducted to date to establish the anticancer potential of BBR. The present review consolidates salient information concerning the promising anticancer activity of this compound.
Effects of Berberine and Its Derivatives on Cancer: A Systems ...
网页2020年1月15日 · Berberine decreased breast cancer cell migration and chemokine expression. This was determined by wound healing assays and RNA analysis of chemokine receptors in MCF-7 breast cancer cells (Ahmadiankia et al., 2016). Berberine has been proven to increase the anti-tumor effects of tamoxifen (TAM) in drug-sensitive MCF-7 and drug-resistant MCF-7 ...
Berberine as a Potential Anticancer Agent: A Comprehensive Review
网页2021年12月4日 · Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial amount of research has been conducted to date to establish the anticancer potential of BBR. The present review consolidates salient information concerning the promising anticancer activity of this compound.
Advances in the study of berberine and its derivatives: a ... - Nature
网页Studies have already shown that berberine has potential anti-tumor activities in the digestive system including nasopharyngeal carcinoma (NPC), gastric cancer, liver …
The Anti-Cancer Mechanisms of Berberine: A Review - PubMed
网页2020年1月30日 · BBR exerts its anti-inflammation and antioxidant properties, and also regulates tumor microenvironment. This review emphasized that BBR as a potential anti-inflammation and antioxidant agent, also as an effective immunomodulator, is expected to be widely used in clinic for cancer therapy.
Unlocking the potential of Berberine: Advancing cancer therapy …
网页2024年8月10日 · This review focuses on Berberine (BBR), an isoquinoline alkaloid found in various medicinal plants, which has garnered attention in the field of oncology for its anticancer potential either alone or in combination with other compounds and its ability to modulate chemoresistance, acting as a natural chemosensitizer.
Berberine, an epiphany against cancer - PubMed
网页2014年8月15日 · In recent years, berberine has been reported to inhibit cell proliferation and to be cytotoxic towards cancer cells. Based on this evidence, many derivatives have been synthesized to improve berberine efficiency and selectivity; the results so far obtained on human cancer cell lines support the idea that they could be promising agents for ...
Berberine - Memorial Sloan Kettering Cancer Center
网页2023年6月12日 · Berberine is a compound found in some plants that may lower cholesterol, triglycerides, and blood sugar levels. Learn about its potential uses, side effects, and how it may affect oral chemotherapy drugs from Memorial Sloan Kettering Cancer Center.
The Anti-Cancer Mechanisms of Berberine: A Review - Taylor
网页2020年1月30日 · Berberine (BBR) has been extensively studied in vivo and vitro experiments. BBR inhibits cell proliferation by regulating cell cycle and cell autophagy, and promoting cell apoptosis. BBR also inhibits cell invasion and metastasis by suppressing EMT and down-regulating the expression of metastasis-related proteins and signaling pathways.
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