Ganciclovir and valganciclovir: An overview - UpToDate
网页2024年5月16日 · Ganciclovir was the first antiviral agent approved for the treatment of cytomegalovirus (CMV) infection. It is widely used for the treatment of CMV infections among patients with impaired cell-mediated immunity, particularly persons with poorly controlled and advanced human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS ...
Valganciclovir for Symptomatic Congenital Cytomegalovirus Disease
网页2015年3月5日 · The treatment of symptomatic congenital cytomegalovirus (CMV) disease with intravenous ganciclovir for 6 weeks has been shown to improve audiologic outcomes at 6 months, but the benefits wane...
Optimizing Antiviral Dosing for HSV and CMV Treatment in ...
网页2023年1月3日 · Ganciclovir is the first antiviral drug to be effective in the treatment of CMV disease in humans. In tissue culture, ganciclovir exhibits excellent antiviral activity against CMV, HSV type 1 and 2, Epstein–Barr virus, varicella-zoster virus and, human herpesvirus 6 [ …
Cytomegalovirus - StatPearls - NCBI Bookshelf
网页2023年8月8日 · Patients without CMV infection who receive organ transplants from CMV-infected donors should receive prophylactic treatment with valganciclovir or ganciclovir, and regular serological monitoring; if treated, the early establishment of a potentially life-threatening infection can be avoided.
Management of ganciclovir resistance cytomegalovirus infection with CMV ...
网页Cytomegalovirus (CMV) disease caused by genetically resistant CMV poses a major challenge in solid organ transplant recipients, and the development of resistance is associated with increased morbidity and mortality. Antiviral resistance affects 5%-12% of patients following ganciclovir (GCV) therapy, but is more common in individuals with ...
Ganciclovir | New England Journal of Medicine
网页Ganciclovir is a nucleoside analogue of guanosine, a homologue of acyclovir, and the first antiviral drug to be effective in the treatment of cytomegalovirus (CMV) disease in humans. 1–4 It...
Ganciclovir (Oral Route, Intravenous Route) Description ... - Mayo Clinic
网页2024年8月1日 · Ganciclovir is used to treat the symptoms of cytomegalovirus (CMV) infection of the eyes in people whose immune system is not working fully. This includes patients with acquired immune deficiency syndrome (AIDS). Ganciclovir will not cure this eye infection, but it may help to keep the symptoms from becoming worse.
Successful treatment of cytomegalovirus retinitis with oral ...
网页2022年10月3日 · In addition, Valganciclovir, an oral prodrug of Ganciclovir, has been shown as effective as Ganciclovir for CMV remission in HIV positive patients . In the present study, we report a case...
Standard ganciclovir dosing results in slow decline of …
网页2021年11月23日 · Ganciclovir, either intravenously administered or orally administered as the pro-drug valganciclovir, is commonly used for prophylaxis and treatment of CMV infection. 8, 9 A pre-emptive approach rather than daily prophylactic therapy minimizes exposure to ganciclovir, which often causes significant adverse events, such as myelosuppression (e.g ...
Treatment of cytomegalovirus anterior segment infection with ...
网页2021年2月4日 · In patients with positive CMV DNA in the aqueous humor after repeated tap, we changed the treatment strategy and prescribed topical ganciclovir for recurrence of CMV anterior segment...
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