Oxidative Stress and Programmed Cell Death in Yeast
网页2012年6月21日 · This review will discuss oxidative stress in yeast, in terms of sources of reactive oxygen species (ROS), their molecular targets, and the metabolic responses elicited by cellular ROS accumulation. Responses of yeast to accumulated ROS include upregulation of antioxidants mediated by complex transcriptional changes, activation of …
Biological autoluminescence for assessing oxidative processes in yeast ...
网页2021年5月25日 · In living organisms, incomplete reduction of \ ( {\text {O}}_2\) during respiration is considered to be a typical source of ROS. However, ROS are also naturally produced during fatty acid...
The Response to Heat Shock and Oxidative Stress in
网页2011年2月21日 · Yeast cells respond to ROS by altering the expression of genes encoding antioxidant defense mechanisms and genes encoding enzymes, which repair and detoxify the resulting cellular damage. This forms the basis for inducible adaptive responses, where for example, cells treated with a low dose of oxidant can adapt to become resistant to a ...
Response Mechanisms to Oxidative Stress in Yeast and
网页2018年10月17日 · Yeast cell death induced by ROS-associated stress stimuli can occur via two alternative pathways: Yca1-dependent apoptosis or Yca1-independent apoptosis (Madeo et al. 2009). These two pathways differ from each other because Yca1-independent apoptosis occurs without cytochrome c release, which requires Yca1p (Perrone et al. 2008 ).
Reactive oxygen species, heat stress and oxidative-induced ...
网页This manuscript describes the main mitochondrial sources of ROS and the antioxidant defences involved to prevent oxidative damage in all the mitochondrial compartments. It also deals with discussions concerning the cytotoxic effect of heat stress, mitochondrial heat-induced alterations, as well as heat shock protein (HSP) expression as a ...
Heat-induced longevity in budding yeast requires respiratory …
网页2018年9月17日 · Here, we found that a metabolic switch from glycolysis to aerobic respiration, and the resulting increase in the reactive oxygen species (ROS) levels trigger the activation of the pentose phosphate pathway (PPP) in budding yeast Saccharomyces cerevisiae cells undergoing mild HS. We further show that this change in …
Slowest possible replicative life at frigid temperatures for yeast
网页2022年12月6日 · By monitoring budding yeast’s slowed-down life at frigid temperatures and with modeling, we establish that Reactive Oxygen Species (ROS) and a global gene-expression speed quantitatively...
Oxidative stress and programmed cell death in yeast
网页Responses of yeast to accumulated ROS include upregulation of antioxidants mediated by complex transcriptional changes, activation of pro-survival pathways such as mitophagy, and programmed cell death (PCD) which, apart from apoptosis, includes pathways such as autophagy and necrosis, a form of cell death long considered accidental and uncoordin...
Yeast signaling pathways in the oxidative stress response
网页2005年1月6日 · In this article, we present an overview of the signaling pathways that sense oxidative stress and induce expression of various anti-oxidant genes in the budding yeast Saccharomyces cerevisiae, the fission yeast Schizosaccharomyces pombe and the pathogenic yeast Candida albicans.
Increased mitochondrial respiration promotes survival from …
网页2018年5月23日 · In yeast and mammalian cells lacking Ire1 or calcineurin, respiratory activation is impaired in response to ER stress; accumulation of mitochondrial reactive oxygen species (ROS) triggers cell...
- 某些结果已被删除
跳至内容