Leucovorin Calcium - NCI - National Cancer Institute
网页Leucovorin calcium is a type of drug called a folic acid analog, which means it is similar to the vitamin folic acid. It is used in combination with certain chemotherapy drugs to enhance their ability to kill cancer cells (for example, fluorouracil) or to lessen their harmful side effects (for example, methotrexate).
Leucovorin Calcium - Uses, Side Effects, and More - WebMD
网页Leucovorin Calcium - Uses, Side Effects, and More. Generic Name (S): leucovorin calcium. Uses. This medication is used to treat or prevent serious blood cell disorders (such as...
Leucovorin Uses, Side Effects & Warnings - Drugs.com
网页2024年7月29日 · Leucovorin is used to reduce the side effects of large doses or accidental overdose of medications that can reduce the effects of folic acid in the body. This includes methotrexate (Rheumatrex), pyrimethamine (Daraprim), trimethoprim (Trimpex, Proloprim), and …
Leucovorin (Oral Route, Intravenous Route, Injection Route)
网页Leucovorin is used as an antidote to the harmful effects of methotrexate (a cancer medicine) that is given in high doses. It is used also to prevent or treat certain kinds of anemia. Leucovorin acts the same way in the body as …
Leucovorin - StatPearls - NCBI Bookshelf
网页2023年7月3日 · Leucovorin is a medication used in the treatment of methotrexate toxicity and chemotherapy regimens. Leucovorin is a folate analog. This activity reviews the indications, action, and contraindications for leucovorin as a valuable agent in the reversal of methotrexate toxicity and as a part of chemotherapy regimens.
Leucovorin Calcium - Memorial Sloan Kettering Cancer Center
网页2022年12月12日 · Patient & Community Education. Leucovorin Calcium. Adult Medication. This information from Lexicomp ® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider. Brand Names: Canada. Lederle Leucovorin; MINT-Leucovorin; RIVA …
Leucovorin Calcium - Medicine.com
网页2020年6月21日 · Leucovorin calcium is a reduced form of folic acid, leucovorin supplies the necessary cofactor blocked by methotrexate. Leucovorin actively competes with methotrexate for transport sites, displaces methotrexate from intracellular binding sites, and restores active folate stores required for DNA/RNA synthesis.
DailyMed - LEUCOVORIN CALCIUM tablet
网页2023年9月11日 · Leucovorin Calcium Tablets are indicated to diminish the toxicity and counteract the effects of impaired methotrexate elimination and of inadvertent overdosages of folic acid antagonists. CONTRAINDICATIONS. Leucovorin is improper therapy for pernicious anemia and other megaloblastic anemias secondary to the lack of vitamin B12.
LEUCOVORIN CALCIUM injection, powder, lyophilized, for solution - DailyMed
网页2022年11月9日 · Leucovorin Calcium for Injection is indicated in the treatment of megaloblastic anemias due to folic acid deficiency when oral therapy is not feasible. Leucovorin Calcium for Injection is also indicated for use in combination with 5-fluorouracil to prolong survival in the palliative treatment of patients with advanced colorectal cancer.
Leucovorin: Uses, Interactions, Mechanism of Action
网页Leucovorin is a folate analog used to treat the toxic effects of methotrexate and other folate antagonists, to treat megaloblastic anemia, and to provide palliative treatment of colorectal cancer. Brand Names. EnBrace HR, EnLyte, Lederle Leucovorin. Generic Name. Leucovorin. DrugBank Accession Number. DB00650. Background.
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