Strategic application of liposomal system to R-α-lipoic acid for …
网页The RLA-loaded liposomal system might be a promising carrier for poorly water-soluble materials with poor stability under acidic conditions, as well as RLA, to improve their oral absorption and nutraceutical properties.
Alpha-Lipoic Acid - StatPearls - NCBI Bookshelf - National …
网页2024年1月26日 — Alpha-lipoic acid (ALA) is a supplement for managing chronic diseases characterized by oxidative stress, notably diabetic neuropathy, and demonstrates promise in slowing the onset of metabolic syndrome through antioxidant properties.
An Overview of the Antioxidant Effects of Ascorbic Acid and Alpha ...
网页2020年4月25日 — This mini review focuses on the liposomal delivery of selected antioxidants, namely ascorbic acid (AA) and alpha-lipoic acid (ALA). The contribution of these nanocarriers in enhancing the antioxidant effect of AA and ALA and consequently their anticancer potentials will be demonstrated.
Molecular and Therapeutic Insights of Alpha-Lipoic Acid as a …
网页2023年2月7日 — Alpha-lipoic acid is an organic, sulfate-based compound produced by plants, humans, and animals. As a potent antioxidant and a natural dithiol compound, it performs a crucial role in mitochondrial bioenergetic reactions.
Nanotechnological Approaches to Enhance the Potential of α-Lipoic Acid …
网页2024年6月9日 — α-lipoic acid is a naturally occurring compound with potent antioxidant properties that helps protect cells and tissues from oxidative stress. Its incorporation into nanoplatforms can affect factors like bioavailability, stability, reactivity, and targeted delivery.
Strategic application of liposomal system to R-α-lipoic acid for …
网页2022年8月9日 — R-α-lipoic acid (RLA) and dihydrolipoic acid (DHLA), a reduced form of RLA, are potent endogenous antioxidants that can reduce oxidative damage. Despite their numerous nutraceutical potentials, clinical applications of RLA are still limited due to its poor solubility and stability problems.
Encapsulation of Alpha-Lipoic Acid in Functional Hybrid ... - MDPI
网页2022年3月24日 — Encapsulation of Alpha-Lipoic Acid in Functional Hybrid Liposomes: Promising Tool for the Reduction of Cisplatin-Induced Ototoxicity. by. Manuela Curcio. 1, Giuseppe Cirillo. 1,*, Rosario Amato. 2, Lorenzo Guidotti. 2, Diana Amantea. 1, Michele De Luca. 1, Fiore Pasquale Nicoletta. 1, Francesca Iemma. 1 and. Mercedes Garcia-Gil. 2,3. 1.
[Liposomal form of lipoic acid: preparation and determination of ...
网页Optimal conditions for obtaining phosphatidylholine (PC) liposomes with lipoic acid (LA) are chosen that lead to the formation of nanoparticles with a size of 175¸284 nm with efficiency (extent) of inclusion of LA in liposomes equal 85% and characterized by a slow release of substance from the nanop ….
R-Alpha Lipoic Acid - LivOn Labs
网页Learn about Alpha Lipoic Acid skin care benefits and why the Universal Antioxidant is becoming part of the standard anti-aging regimen. FREE SAMPLES WITH FIRST …
Liposomal encapsulation of omega‐3 fatty acid and α‐lipoic acid ...
网页2021年10月23日 — Abstract. α-linolenic acid (ALA) and α-lipoic acid (LA) are well-known bioactives with salutary effects and are potential health supplements. However, they are susceptible to oxidation.