Expanded characterization of in vitro polarized M0, M1, and M2 …
网页2023年3月2日 · Polarization of macrophages to M0-, M1-, and M2-like phenotypes significantly changes cytokine secretion. We measured the concentrations of secreted cytokines and immune mediators in our different macrophage subsets that have previously been shown to differentiate macrophage subtypes .
An M0 macrophage-related prognostic model for hepatocellular …
网页2022年7月19日 · The role of M0 macrophages and their related genes in the prognosis of hepatocellular carcinoma (HCC) remains poorly characterized. Multidimensional bioinformatic methods were used to construct a risk score model using M0 macrophage-related genes (M0RGs).
巨噬细胞极化标志物 - 知乎 - 知乎专栏
网页2023年12月26日 · 巨噬细胞（Macrophages，缩写为mø）是一种位于组织内的白血球，也称组织细胞（histocyte），源自单核细胞，由血液中的单核细胞穿过血管后分化而成。 单核细胞进入结缔组织后，体积增大，内质网和…
The generation, activation, and polarization of monocyte-derived ...
网页2023年4月18日 · Schematically, three main macrophage subpopulations coexist in human tissues: naïve macrophages also called M0, pro-inflammatory macrophages referred as M1 macrophages, and anti-inflammatory macrophages also known as M2 macrophages.
Label-free macrophage phenotype classification using machine …
网页2023年3月30日 · In this work, we investigated macrophage autofluorescence as a distinct feature for classifying six different macrophage phenotypes, namely: M0, M1, M2a, M2b, M2c, and M2d. The identification...
Macrophages in immunoregulation and therapeutics
网页2023年5月22日 · Macrophages possess binary M1/M2 macrophage polarization settings, which perform a central role in an array of immune tasks via intrinsic signal cascades and, therefore, must be precisely...
Expanded characterization of in vitro polarized M0, M1, and M2
网页2023年3月2日 · Polarization of macrophages to M0-, M1-, and M2-like phenotypes significantly changes cytokine secretion. We measured the concentrations of secreted cytokines and immune mediators in our different macrophage subsets that have previously been shown to differentiate macrophage subtypes .
Expanded characterization of in vitro polarized M0, M1, and M2 …
网页2023年3月2日 · Peripheral blood monocytes from healthy volunteers were differentiated into hMDM and polarized with either IFN-γ + LPS (M1) or IL-4 (M2). As expected, our M0, M1, and M2 hMDMs exhibited cell surface marker, phagocytosis, and gene expression profiles indicative of their different phenotypes.
In-Depth Characterization of Monocyte-Derived Macrophages …
网页2019年2月13日 · We applied this assay to distinct monocyte derived macrophage (MDM) populations and found that prototypic M2-like MDMs phagocytose more E. coli than M1-like MDMs.
Differentiation and Functional Comparison of Monocytes and Macrophages …
网页2019年6月11日 · We developed an efficient protocol to derive monocytes and macrophages from human induced pluripotent stem cells (hiPSCs) and performed a functional comparison with PB-derived cells. hiPSC-derived monocytes were functional after cryopreservation and exhibited gene expression profiles comparable with …