Systemic mastocytosis - Symptoms and causes - Mayo Clinic
网页2020年11月20日 · When you have systemic mastocytosis, excess mast cells build up in your skin, bone marrow, digestive tract or other body organs. When triggered, these mast cells release substances that can cause signs and symptoms similar to those of an allergic reaction and, sometimes, severe inflammation that may result in organ damage.
Mastocytosis: Types, Symptoms & Treatment - Cleveland Clinic
网页Mastocytosis (pronounced “mas-to-sy-TOE-sis”) is a rare disease that happens when your body makes too many mast cells. Mast cells are white blood cells and part of your immune system. They go to work when intruders like bacteria and allergens threaten your body. Mast cells react to intruders by releasing histamine.
Systemic mastocytosis - Diagnosis and treatment - Mayo Clinic
网页2020年11月20日 · The five main types of systemic mastocytosis include: Indolent systemic mastocytosis. This is the most common type and usually doesn't include organ dysfunction. Skin symptoms are common, but other organs may be affected, and the disease may worsen slowly over time. Smoldering systemic mastocytosis.
Systemic Mastocytosis: Symptoms & Treatment - Cleveland Clinic
网页2022年10月28日 · Systemic mastocytosis is a rare blood disorder. It happens when your body makes abnormal mast cells. Mast cells are white blood cells and part of your immune system. They’re first responders when allergens and other intruders attack your body.
Systemic Mastocytosis - StatPearls - NCBI Bookshelf
网页2023年7月4日 · Systemic mastocytosis is an aggressive disorder characterized by the release of numerous vasoactive cell mediators due to excessive activity of mast cells, which results in a wide variety of symptoms. Symptoms include anaphylaxis, flushing, nonspecific GI as well as neuropsychiatric complaints.
Updated Diagnostic Criteria and Classification of Mast Cell …
网页2021年10月13日 · Mastocytosis is a hematologic neoplasm characterized by expansion and focal accumulation of neoplastic mast cells (MC) in diverse organs, including the skin, bone marrow (BM), spleen, liver, and gastrointestinal tract.
Mastocytosis - Mastocytosis - Merck Manual Consumer Version
网页Mastocytosis is an uncommon abnormal accumulation of mast cells in the skin and sometimes in various other parts of the body. People may have itchy spots and bumps, flushing, digestive upset, and sometimes bone pain or anaphylactic and anaphylactoid reactions.
Systemic mastocytosis - MedlinePlus
网页Description. Systemic mastocytosis is a blood disorder that can affect many different body systems. Individuals with the condition can develop signs and symptoms at any age, but it usually appears after adolescence.
Systemic Mastocytosis - American Academy of Allergy, Asthma …
网页Mastocytosis is a disorder in which abnormal mast cells are increased in one or more organs. In this condition the growth of mast cells is poorly controlled, sometimes as the result of mutations that produce clones, or identical copies, of cells.
Mastocytosis—A Review of Disease Spectrum with Imaging …
网页2021年10月12日 · Mastocytosis is an uncommon disorder with an estimated prevalence of 1 in 10,000 persons characterized by abnormal proliferation and accumulation of clonal mast cells [1]. Organ involvement and clinical features further classify the disease as cutaneous mastocytosis (CM) and systemic mastocytosis (SM).