Mastocytosis: Types, Symptoms & Treatment - Cleveland Clinic
网页Mastocytosis is a rare condition that happens when your body makes abnormal mast cells that multiply uncontrollably, affecting your skin and organs. Most people with mastocytosis manage its symptoms by knowing what …
Mastocytosis - DermNet
网页Mastocytosis is a diverse group of disorders characterised by the expansion and accumulation of mast cells in one or more organ systems. It can affect the skin, bone marrow, liver, spleen, gastrointestinal tract, or lymph nodes. In 2022, the World Health Organisation (WHO) categorised three main types of mastocytosis:
Systemic mastocytosis - Symptoms and causes - Mayo Clinic
网页2020年11月20日 · When you have systemic mastocytosis, excess mast cells build up in your skin, bone marrow, digestive tract or other body organs. When triggered, these mast cells release substances that can cause signs and symptoms similar to those of an allergic reaction and, sometimes, severe inflammation that may result in organ damage.
Systemic Mastocytosis - StatPearls - NCBI Bookshelf
网页2023年7月4日 · Systemic mastocytosis is an aggressive disorder characterized by the release of numerous vasoactive cell mediators due to excessive activity of mast cells, which results in a wide variety of symptoms. Symptoms include anaphylaxis, flushing, nonspecific GI as well as neuropsychiatric complaints.
Mastocytosis (cutaneous and systemic) in adults ... - UpToDate
网页2024年7月11日 · Mastocytosis describes a group of rare disorders in which there is pathologic accumulation of mast cells in tissues. These diseases can be limited to the skin (cutaneous mastocytosis [CM]) or involve extracutaneous tissues (systemic mastocytosis [SM]). The evaluation and diagnosis of the different forms …
Cutaneous mastocytosis treatment: strategies, limitations and ...
网页2018年8月13日 · In cutaneous mastocytosis (CM), mast cells infiltration is limited to the skin, whereas in systemic mastocytosis (SM) internal organs are involved. The first-line treatment in CM is antimediator therapy (mainly H1 and H2 antihistamines) and short-term topical corticosteroids.
Updated Diagnostic Criteria and Classification of Mast Cell …
网页2021年10月13日 · Mastocytosis is a hematologic neoplasm characterized by expansion and focal accumulation of neoplastic mast cells (MC) in diverse organs, including the skin, bone marrow (BM), spleen, liver, and gastrointestinal tract.
Mastocytosis: What It Looks Like, Causes, and Symptoms
网页2023年8月22日 · Mastocytosis is a genetic immune disorder by which mast cells grow abnormally and build up in the skin and other organs. The condition, a type of mast cell disease, causes a number of symptoms, including flushed skin, gastrointestinal issues, and liver and spleen enlargement.
Systemic mastocytosis - Diagnosis and treatment - Mayo Clinic
网页2020年11月20日 · The five main types of systemic mastocytosis include: Indolent systemic mastocytosis. This is the most common type and usually doesn't include organ dysfunction. Skin symptoms are common, but other organs may be affected, and the disease may worsen slowly over time. Smoldering systemic mastocytosis.
Systemic Mastocytosis: Symptoms & Treatment - Cleveland Clinic
网页2022年10月28日 · People with systemic mastocytosis may develop raised spots or rashes on their skin. When touched or stroked, the area of skin affected by the rash may turn red and start to itch or swell. What is systemic mastocytosis? Systemic mastocytosis is a rare blood disorder. It happens when your body makes abnormal mast cells.