Beyond Pellagra—Research Models and Strategies Addressing …
网页2023年2月3日 · Pellagra, as the clinical disease caused by NAD deficiency, is characterized by a range of D symptoms: The first D stands for the eponymous clinical symptom of sun-sensitive dermatitis, which led to the use of the Italian term “pelle agra” (meaning rough skin) as a basis for the name for the disease.
网页Pellagra is a clinical syndrome characterised by dermatitis, diarrhoea dementia and if untreated may result in death. A deficiency of niacin causes it. Pellagra was initially described by a Spanish Physician Gasper Casal. Previously nutritional deficiency was the leading and recognised cause of pellagra in the world. This is no longer the case
网页Abstract: Pellagra is a rare disease caused by niacin deficiency or a disruption of its metabolism. Its manifestations are dermatitis with pronounced photosensitivity, gastrointestinal symptoms, and neurop-sychiatric ailments. Currently pellagra is developed in people who chronically abuse alcohol or are treated
Diagnosis and Treatment of Pellagra - Medscape Education
网页4 天之前 · Pellagra is the late stage of severe niacin deficiency. Primary pellagra results from inadequate nicotinic acid (ie, niacin) and/or tryptophan intake in the diet. Secondary pellagra occurs when adequate quantities of niacin are present in the diet, but other diseases or conditions interfere with its absorption and/or processing.
The Bacteriological Divide: Pellagra in Italy and the United States ...
网页2023年5月1日 · At the 73rd meeting of the British Medical Association, held in Leicester that year, Sambon voiced his hypothesis on the aetiology and spread of pellagra, using a detailed survey of pellagra’s spread to identify a possible vector or agent.
Pellagra: A Non-Eradicated Old Disease - PMC - National Center …
网页2014年3月3日 · Pellagra is a nutritional disorder caused by niacin (vitamin B3) deficiency, which leads to systemic disease with clinical manifestations from the skin, gastrointestinal tract and the nervous system. 1-3 Niacin forms into nicotinic acid and nicotinamide, which serve as precursors of two important coenzymes of cellular metabolism, namely ...
Pellagra Pre-Goldberger: Rupert Blue, Fleming Sandwith, and The ...
网页In February 1914, Surgeon General Rupert Blue of the US Public Health Service made Goldberger his chief pellagra investigator. As the story is usually told, pellagra was widely considered an infectious disease and most people, including Goldberger himself, anticipated that he would find the causative germ.
Pellagra: a Still Present Disease | SN Comprehensive ... - Springer
网页2021年5月1日 · Pellagra is a vitamin disorder caused by deficiency in vitamin B3, also called niacin. It is a multi-systemic disorder that most commonly involves skin, nervous system, and gastrointestinal tract. Indeed, pellagra is often said to consist of “the four Ds”: dementia, diarrhea, dermatitis, and death.
Diagnosis and Treatment of Pellagra - Medscape Education
网页3 天之前 · Pellagra is typically a disease that occurs in adults. Pellagra may develop in adolescents and young children if they are exposed to a pellagragenic diet. Pellagra rarely occurs in infants. Historically, dermatitis associated with kwashiorkor was mistaken for infantile pellagra.
Diagnosis and Treatment of Pellagra - Medscape Education
网页2010年9月30日 · The therapeutic response to niacin in a patient with the typical symptoms and signs of pellagra establishes the diagnosis. Blood counts (anemia), findings of hypoproteinemia, higher levels of serum calcium and lower levels of serum kalium and phosphorus, liver function test results, and serum porphyrin levels …