SEVtras delineates small extracellular vesicles at droplet resolution ...
网页2023年12月4日 · Small extracellular vesicles (sEVs) are emerging as pivotal players in a wide range of physiological and pathological processes. However, a pressing challenge has...
The identification of novel small extracellular vesicle (sEV ...
网页2022年9月27日 · Small extracellular vesicles (sEVs) are nano-sized vesicles secreted from various cells that contain bioactive metabolites and function as key regulators for intercellular communication. sEVs modulate diverse biological and pathological processes in the body, and the amount of circulating sEVs has been reported to …
Single vesicle analysis reveals the release of tetraspanin positive ...
网页2023年2月28日 · Small extracellular vesicles (sEVs) are released from all cell types and participate in the intercellular exchange of proteins, lipids, metabolites and nucleic acids. Proteomic, flow cytometry and nanoparticle tracking analyses suggest sEVs are released into circulation with exercise.
Small extracellular vesicles isolation and separation: Current ...
网页2022年9月6日 · Small extracellular vesicles (sEVs) usually refers to EVs smaller than 200 nm in diameter, and are the representative EV types most widely studies for their roles in different physiological and pathological conditions.
Small extracellular vesicles (sEVs)-based gene delivery platform for ...
网页2024年4月28日 · Small extracellular vesicles (sEVs) are naturally occurring vesicles that have the potential to be manipulated to become promising drug delivery vehicles for on-demand in vitro and in vivo gene editing.
Expression of the αVβ3 integrin affects prostate cancer sEV cargo …
网页2024年8月6日 · This paper focuses on small extracellular vesicles (sEVs), which are of endosomal or non-endosomal origin and are characterized by proteins such as CD9, CD81 and TSG101 (Mathieu et al., 2019). Most cell types, including cancer cells, release sEVs as a means of cell-cell communication (Peinado et al., 2017).
Blood concentrations of small extracellular vesicles are determined …
网页2019年11月26日 · Small extracellular vesicles (sEVs) are important mediators of cell–cell communication with respect to diverse physiological processes. To further understand their physiological roles, understanding blood sEV homoeostasis in a quantitative manner is desired.
Fluorescence-tagged salivary small extracellular vesicles as a …
网页2023年9月4日 · The sEV suspension from precipitation is followed by an ultrafiltration step that aids in concentrating the sEV suspension and removal of traces of precipitant and very small protein contaminants. We identified the purity and efficient isolation of sEV using CD63 (surface marker) expression in the sEV pellet and supernatant.
Small Extracellular Vesicles From Spared Nerve Injury Model and …
网页2023年9月1日 · Small extracellular vesicles (sEVs) from SNI model and sham control mice have distinct miRNAs. •. Uptake of sEVs from SNI model or sham control mice induces gene expression changes in primary microglia. •. Magnitude of cytokine release upon sEV uptake is dependent on type of injury and sex of sEV donor mice. •.
Impact of isolation methods on the biophysical heterogeneity of …
网页2020年8月7日 · Successful sEV isolation was confirmed by electron microscopy, immune labeling (CD63, CD81 and CD9), and enrichment of sEV associated proteins determined using Mass Spectrometry (Supplemental...
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