InnoCare Pharma (HKEX: 09969; SSE: 688428), a leading biopharmaceutical company focusing on the treatment of cancer and autoimmune diseases, announced today the approval of the Investigational New ...

Recent research addresses this gap by demonstrating that caspase-2 directly processes BID, initiating the mitochondrial pathway of apoptosis. Moreover, the team discovered HUHS015, a compound that ...

Researchers from the University of Alabama at Birmingham have identified a promising new combination therapy for metastatic ...

Bile acids are essential signaling molecules derived from cholesterol metabolism in the liver and are crucial for the ...

InnoCare Pharma gets Chinese nod to begin clinical trial of BCL2 inhibitor ICP-248 for acute myeloid leukaemia: Beijing Friday, September 20, 2024, 18:00 Hrs [IST] InnoCare Pharma ...

The main goal of our laboratory is the identification and characterization of signal transduction pathways that cause the dysregulation of growth and inhibition of apoptosis that characterize advanced ...

The quality and quantity of the ceramide response, in combination with other signals, determines whether adaptation or apoptosis ensues. This pathway is evolutionarily conserved and is obligate for ...

A simple blood test has been shown to be 98% accurate at distinguishing between patients with ALS and those without the ...

MDA5 is a critical cytoplasmic RNA sensor capable of triggering type I interferon pathways. This study shows that the E3 ...

Focusing on 19 “biodomains”—biological processes such as immune response, synaptic function, lipid metabolism, mitochondrial ...

The discovery of the Bcl-2 protein family, as well as p53 and its involvement in regulating apoptosis, and the CD95 (also known as FAS or APO1) pathway, led to an understanding of the molecular ...