The discovery of the Bcl-2 protein family, as well as p53 and its involvement in regulating apoptosis, and the CD95 (also known as FAS or APO1) pathway, led to an understanding of the molecular ...

本文已于2024年9月2日被撤回： 本文发表后，一位热心的读者向编辑指出，第3763页图1D中显示的某些细胞凋亡测定数据，与另一篇由不同研究机构的不同作者以不同形式提交发表的文章（图3A）中的数据惊人地相似。鉴于上述有争议的数据在提交给《 ...

综上，研究揭示了微塑料导致脱发的潜在机制，微塑料会诱导氧化应激水平，导致毛囊细胞细胞凋亡，进而导致毛囊内细胞间紧密连接受损，从而导致脱发。值得注意的是，老化的微塑料具有更强的毒性。

InnoCare Pharma gets Chinese nod to begin clinical trial of BCL2 inhibitor ICP-248 for acute myeloid leukaemia: Beijing Friday, September 20, 2024, 18:00 Hrs [IST] InnoCare Pharma ...

Bile acids are essential signaling molecules derived from cholesterol metabolism in the liver and are crucial for the ...

MDA5 is a critical cytoplasmic RNA sensor capable of triggering type I interferon pathways. This study shows that the E3 ...

occurs either by degradation of sphingomyelin or by de novo synthesis. The quality and quantity of the ceramide response, in combination with other signals, determines whether adaptation or apoptosis ...

InnoCare Pharma (HKEX: 09969; SSE: 688428), a leading biopharmaceutical company focusing on the treatment of cancer and autoimmune diseases, announced today the approval of the Investigational New ...

The primary interest of our lab is to investigate the molecular mechanisms of apoptosis and how they impact human health and disease ... in combination with our spinning disk confocal microscope to ...

Recent research addresses this gap by demonstrating that caspase-2 directly processes BID, initiating the mitochondrial pathway of apoptosis. Moreover, the team discovered HUHS015, a compound that ...

The main goal of our laboratory is the identification and characterization of signal transduction pathways that cause the dysregulation of growth and inhibition of apoptosis that characterize advanced ...