By transforming into more functional exhausted CD8 + T cells, Tpex cells help maintain robust anti-tumor activity. This study ...

One strategy tumors use to ensure survival involves interfering with our inherent immune response.  Effective anti-tumor ...

In a study published in Advanced Functional Materials, a research team from the Shanghai Institute of Materia Medica (SIMM) ...

proliferate to produce "effector" CD8+ T cells that kill cancer cells. Checkpoint blockade immunotherapies, like anti-PD-1 antibodies, can provide such stimulus. The observation that TCF1 ...

Salt could help to boost the immune defense against cancer. This is suggested by the ... sodium has specifically on the activity of human CD8 + T cells," explains Shan Sun, another first author.

T cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogramming and how ...

proliferate to produce "effector" CD8 + T cells that kill cancer cells. Checkpoint blockade immunotherapies, like anti-PD-1 antibodies, can provide such stimulus. The observation that TCF1 ...

Although MDS cells were originally observed in cancer patients and experimental animals >30 years ago, their role as spoilers of anti-tumor immunity ... of CD4 + and CD8 + T lymphocytes ...

in part reflects anti-cancer immunity mediated by transferred donor T cells, but these cells are generally not leukemia-specific and thus can also have harmful side effects. To address this serious ...

proliferate to produce "effector" CD8+ T cells that kill cancer cells. Checkpoint blockade immunotherapies, like anti-PD-1 antibodies, can provide such stimulus. The observation that TCF1 ...