proliferate to produce "effector" CD8+ T cells that kill cancer cells. Checkpoint blockade immunotherapies, like anti-PD-1 antibodies, can provide such stimulus. The observation that TCF1 ...
Although MDS cells were originally observed in cancer patients and experimental animals >30 years ago, their role as spoilers of anti-tumor immunity ... of CD4 + and CD8 + T lymphocytes ...
Salt could help to boost the immune defense against cancer. This is suggested by the ... sodium has specifically on the activity of human CD8 + T cells," explains Shan Sun, another first author.