Lentiviral vectors were created to harness the powerful capacity of HIV to infect cells and stably insert a stretch of genetic material into the cell genome. Their name comes from lentivirus, the ...

Researchers commonly employ lentiviruses to modify cells genetically. However, they must overcome several challenges when using these viruses in the laboratory or clinic. In this episode, Charlene ...

Retroviruses are a sub-category of oncoviruses that include the lentiviruses. Retroviruses are negative single-stranded RNA viruses in which tRNA serves as a primer for the mRNA synthesis. The mRNA is ...

Lentiviruses have the unique ability amongst retroviruses of being able to infect non-cycling cells. Vectors derived from lentiviruses have provided a huge advancement in technology and seemingly ...

In contrast, lentiviruses such as human immunodeficiency virus (HIV) do not depend on host cell mitosis to access the nucleus. As a consequence, lentviruses are able to replicate within non ...

Current projects in the laboratory focus on retroviruses, specifically the lentiviruses of humans and their primate relatives (the human and simian immunodeficiency viruses – HIV and SIV). Among other ...

An injected antiviral medicine, taken twice a year, appears to offer at-risk people near-complete protection against HIV ...

The ARViS robotic system automates virus injections into the brain with remarkable precision and minimal bleeding, advancing ...

Based on the use of recombinant oncoretroviruses and lentiviruses, we are investigating how to control transgene expression in vivo in hematopoietic stem cells and how to augment immune responses ...

Adeno-associated viruses (AAV), lentiviruses, retroviruses, herpes viruses, adenoviruses and other viral vectors are used in gene and cell treatments to transfer genes. As infection with the ...

Researchers discovered that interferon-stimulated SAMD9L restricts HIV-1 and other lentiviruses by inhibiting viral translation and endosomal trafficking, while SAMD9 enhances HIV-1 replication.

VANCOUVER - Construction of Vancouver's first indoor supervised site for people who inhale illicit drugs is complete in the city's Downtown Eastside and its executive director says people could start ...