Innovative research has provided compelling evidence that perceived stress can directly trigger the relapse of psoriatic skin ...

The lesions in TMEP are not pruritic and do not produce Darier's sign because mast cell proliferation may not be sufficient to produce significant degranulation (Alto & Clarcq, 1999; Hogan & Lewis ...

particularly through mast cell degranulation," explains Professor Amos Gilhar, lead researcher from the Skin Research ...

When a mast cell identifies an antigen (foreign body), it becomes activated and undergoes degranulation, releasing these ...

Reporting in Nature Medicine, McLachlan and colleagues now reveal a previously unknown role of mast cells (MCs) in the induction of the antigen-specific humoral immune response, and identify MC ...

These substances interact with EP3 receptors in MCs and prevent degranulation, limiting the release of histamine ... And people with allergies stand to gain from these insights. "The activation of ...

The following is a summary of “Clustering of clinical symptoms using large language models reveals low diagnostic specificity of proposed alternatives to consensus mast cell activation syndrome ...

Frontline Science: Corticotropin-releasing factor receptor subtype 1 is a critical modulator of mast cell degranulation and stress-induced pathophysiology. 2017 J Leukoc Biol. pii: jlb.2HI0317-088RR.

MRGPRX2 is most abundantly found on mast cells and peripheral sensory neurons. MRGPRX2 can trigger IgE-independent activation (degranulation) via multiple ligands, which can lead to a variety of ...

Amsterdam, Netherlands) Innovative research has provided compelling evidence that perceived stress can directly trigger ...

A standard treatment for mastocytosis is difficult to apply to individual patients based on the variable clinical course. A general consensus for using antimediator agents such as antihistamines ...

particularly through mast cell degranulation," explains Professor Amos Gilhar, lead researcher of the study. "This is further amplified by corticotropin-releasing hormone (CRH) and NGF, which heighten ...