The aim of this study is to examine the role of mast cell mediators in children with allergic disorders in a two part study. Part 1 of the study will prospectively obtain the values of mast cell ...

She joined Nature Cancer in March 2024 and is based in the London office. Luca did his PhD at the University of Udine (Italy), where he studied the interaction between mast cells and myeloid ...

umin.ac.jp Objective Extracellular ATP mediates mast cell-dependent intestinal inflammation via P2X7 purinoceptors. We have previously shown that CD300f (also called the leucocyte ...

1.comboSC is a scalable toolkit for personalized combination therapy recommendation based on the single-cell sequencing data of cancer patient. 2.comboSC uses a large collection of molecule/drugs, ...

Nonetheless, recent advances in the field have broadened our perspectives regarding the activity of type 2 immunity. For example, ILC2 cells, eosinophils, macrophages, and the cytokines IL-33, ...

In dogs, tigilanol tiglate provides a first-line alternative to surgery in non-metastatic mast-cell tumors, meeting an unmet need in the veterinary market. Its launch as Stelfonta in USA ...

2001). Mast cell sarcoma is rare. There is destructive growth of a local tumor consisting of poorly differentiated mast cells without systemic involvement. Mast cell sarcoma develops into a ...

Researchers enrolled nearly 400 patients with previously untreated, advanced non-small cell lung cancer.

Getting it right is crucial: cells with too many or too few chromosomes can cause cancer, birth defects, or miscarriage. Much of Biggins’s work focuses on kinetochores, structures that connect ...

Gene therapy is a modern medical technology that can be used against both inherited diseases, such as sickle cell disease, or acquired diseases such as cancer. It entails adding new copies of a ...

the department announced that Therapy K9 Chloe will be taking a leave of absence after a routine checkup revealed that a ...

In this research program biotechnology is applied to produce lipid and protein-based drug delivery systems at the nano-scale. These bio-inspired drug delivery systems can consist of recombinant ...