dendritic cells and T-lymphocytes control the effector immune cells, including, eosinophils, neutrophils, mast cells and basophils to promote inflammation and exacerbation of asthma.

Macrophages are a major source of TNF-α with significant contributions from other pro-inflammatory cells including monocytes, dendritic cells, B lymphocytes, T cells, neutrophils, mast cells and ...

Previous research indicates that mast cells, a type of immune cell found in the tissues throughout the body, cause ...

Thurmond has hit some bumps in the road in his journey exploring H4's relation to asthma. Early animal models suggested that this histamine receptor depended on mast cells, white blood cells that ...

We aim to demonstrate proof of concept for the depletion of mast cells with briquilimab as an effective mechanism of action in asthma and to inform potential future studies in the broader asthma ...

In contrast, increased numbers of mast cells occurred in patients with a moderate to marked decrease in bone density. It is possible that bone-marrow mast cells and heparin, which is synthesized ...

J Med Genet., 42, e36 Evidence suggests that mast cells play a central role in the pathophysiology of asthma. Mast cells act as sensors of the environment to defend against damage and infection. They ...

It might be tempting to share your bed with your dog as the weather starts to get colder, but one doctor has said you should ...

Mastocytosis is a rare disorder that develops when the immune system overproduces mast cells—a type of white blood cell that ...

(Nasdaq: JSPR) (Jasper), a clinical stage biotechnology company focused on development of briquilimab, a novel antibody therapy targeting c-Kit (CD117) to address mast cell driven diseases such as ...