In vertebrates, FU and KIF7 function in both cilia formation and Hh signalling. Planar cell polarity (PCP) pathways can control the position of primary cilia, and mammalian homologues of proteins ...

Note that while they may serve as sensory receptor cell specializations, primary cilia can simultaneously support major IFT functions of the cell (Figure 3). The primary cilium has gone from being ...

To define the function of cilium-mediated PD-L1 expression ... while this effect was substantially mitigated by the removal ...

Further, we documented that in each of the five astrocytoma/glioblastoma cell lines studied (U-87 MG, T98G, U-251 MG, U-373 MG, U-138 MG), fully formed primary cilia ...

Pathogenic activating point mutations in the LRRK2 kinase cause autosomal-dominant familial Parkinsońs disease (PD). In cultured cells, mutant LRRK2 causes a deficit in de novo cilia formation and ...

We are investigating the function of these epigenetic modifiers on microtubule and actin dynamics during mitosis and during quiescence, when cells project primary cilia. In particular, our ...

We are investigating cellular mechanisms of tumorigenesis in pheochromocytoma with a current focus on hypoxia induced signaling pathways. Chaperones and environmental modulation of primary cilia ...

Authors should provide at the time of submission a short paragraph explaining why their work justifies urgent publication as a Communication. Ideally, a Full paper in Food & Function should follow ...

The dopamine neurons of the worm possess primary cilia that allow the worm to sense ... is a key regulator of many important ...

Executive function describes a set of cognitive processes and mental skills that help an individual plan, monitor, and successfully execute their goals. The “executive functions,” as they’re ...

A machine-learning method predicts whether a genetic variant is pathogenic and affects certain human tissues. The ...

Primary health care (PHC) is a broader whole-of-society approach with three components: (a) primary care and essential public health functions as a core of integrated health services; (b) ...