New research reveals bacteria age too. They divide unequally, protecting younger cells from damage linked to aging.

A new statistical technique developed by a researcher at the Texas A&M University School of Public Health and colleagues ...

Defense systems found in all complex life (eukaryotes), including us, were likely passed down from “microbial ancestors” ...

Single-cell analysis offers a unique perspective of the genetic and molecular features of individual cells. In this article, ...

▎药明康德内容团队编辑  Join Dr. Peijun Ma’s Lab at St. Jude Children’s Research Hospital (Memphis, TN, U.S.)We are expanding rapidly and seeking passionate, self-driven postdoctoral researchers and graduate stu ...

研究人员发现了与阿尔茨海默病、额颞叶痴呆的行为变异和进行性核上性麻痹共有或不同的脑细胞和基因相关的分子标记。科学家们使用snRNA-seq和snATAC-seq技术分析了死后组织中的不同大脑区域。这些发现强调了不同痴呆症中胶质和神经元组成和基因表达变化的异质性，揭示了共同的和疾病特异性的细胞状态，可能指向新的治疗靶点。

IBCN annual meeting included a keynote lecture by Dr. Niko Beerenwinkel discussing inferring tumor evolution from single-cell data. Although the majority of work has been done in other cancers (ie.

For one particular lineage of breast cancer cells, chemotherapy had the highest overall benefit at 10 to 12 hours into the 24 ...

Age-related musculoskeletal diseases are a significant public health concern that critically impacts the motor functions and the quality of life in the elderly. The musculoskeletal system supports the ...

Interested in the spatial research landscape, technological breakthroughs and future directions? Check out this interview ...

Together, the findings suggested that 17α-estradiol extensively reshaped the cell populations, cellular communication, neuropeptide secretion, and neural synapse activity in aged hypothalamus, which ...