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18 天
【Nature子刊】中国医科大学宫月华团队:细胞衰老相关基因与多种 ...
目前,基于传统的观察性研究,已经确定了特定细胞衰老相关(CSR)基因与多种肿瘤风险之间的关联。例如,EZH2和TOP2A敲低通过诱导细胞衰老,来抑制肝癌发生。IL-1是SASP的关键成分,可促进口腔前体病变的恶性转化。SOX6通过诱导细胞衰老,来抑制 ...
12 天
可抑制肝癌进展!华中科技大学发文:调节肝癌进展的新机制
更吸引人的是,根据NCBI的RNA-seq数据,ITIH1是一种仅在肝脏中表达的蛋白质。除了其治疗潜力,它还可能是HCC的诊断生物标志物。未来的研究应探讨ITIH1在HCC中的潜在诊断价值,并建立一个类似于AFP的临界值,以早期诊断HCC。
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