Children with Down’s syndrome have a 150-fold increased risk of developing leukaemia than those without the condition. Now, ...

A century after Down syndrome was first described, scientists discovered that the root cause of this disorder is a condition called trisomy 21. What strides in research have been made since then?

By Pooja Toshniwal Paharia The study links genetic and regulatory changes to increased erythrocyte production and leukemia ...

The most impactful gene is the apolipoprotein E-e4 gene (APOE-e4) – people who carry two APOE-e4 copies have 12 times the ...

比如这篇文章就报道的是一个男性21三体患者生下了正常后代： Sheridan R, Llerena J, Matkins S, et al. Fertility in a male with trisomy 21[J]. Journal of medical genetics ...

New research shows that DNA replication in early mouse embryos doesn't follow the expected patterns seen in older cells. A ...

Statement highlights include: Trisomy 21, also known as Down syndrome, is a genetic condition that occurs when a person has an extra copy of chromosome 21. According to the American Heart ...

Cell-free DNA test during pregnancy is a non-invasive test that screens for common chromosomal disorders like Down syndrome.

One way in which they fall short is they focus on only the three most common trisomies: Down syndrome (trisomy 21), Trisomy 18 and Trisomy 13. Invasive testing will detect other trisomies ...

Antenatal diagnosis of Trisomy 13 is often made by karyotyping. This is typically performed after an assessment of risk for a chromosomal disorder is made by the maternal healthcare provider.

Dr. Klaus Patau, who has kindly reviewed sets of chromosomes from Group 13–15 of 9 metaphase plates of the propositus, believes that the present case most probably represents trisomy ...

For Gigi Hutchison-Martinez and her mom, inclusion doesn’t mean creating a separate spirit squad so Gigi and other special ...