进一步的机制研究表明,给药的Tregs一旦在受损区域呈现损伤特异性表型。在此过程中,treg显示出与免疫调节和组织愈合相关的基因表达水平增加。进一步的实验表明,Tregs可以导致这些组织中的单核细胞和巨噬细胞切换到抗炎状态,特别是通过分泌白介素-10 (IL-10)等信号分子。
Rutgers Health researchers will enroll primary or secondary progressive multiple sclerosis (p-MS) patients to see if an ...
这两项研究论文得出了同样的结论:食盐可以增强杀伤性T细胞的抗肿瘤免疫力。尤其值得一提的是,Enrico Lugli团队还在小鼠身上证实,仅通过高盐饮食就能增强T细胞的抗癌能力,抑制肿瘤的生长。
早在20多年前,耶鲁大学的研究人员就在人类机体中发现了一种能抑制 免疫 系统的特殊T细胞类型,后来他们发现,这些所谓的调节性T细胞当发生缺陷时就会诱发一些自身免疫性疾病,尤其是 多发性硬化 症(MS,multiple ...
Injecting regulatory T cells or Tregs, which control the body’s immune responses, directly into damaged bone, muscle and skin ...
While past research focused on adjusting a patient's immune cells, new studies explore delivering specific cells.
胶质母细胞瘤(GBM)被归类为四级胶质瘤,是中枢神经系统常见的内源性恶性肿瘤。尽管实施了包括较大限度手术切除、放疗和以替莫唑胺(TMZ)为基础的化疗联合后续序贯TMZ治疗的标准治疗方案,但新诊断的GBM患者的平均总生存(OS)时间仅为14.6个月。胶质母细胞瘤干细胞(GSCs)是一小部分具有自我更新和多向分化能力的GBM细胞,被认为是GBM肿瘤发生和发展的责任方。GSCs还具有辐射抵抗、化疗抵抗、 ...
根据中国药物临床试验登记与信息公示平台,安进已经在中国启动AMG 451的多项临床研究,适应症包括特应性皮炎和哮喘。此次AMG 451再次获批临床,意味着该产品即将在新的结节性痒疹疾病领域进行临床探索。
Despite not being everyones favourite vegetable bitter gourd provides various benefits for skin hair and overall health ...
A team of scientists from the Perelman School of Medicine at the University of Pennsylvania and Aum Biotech LLC have described the development of a novel cancer immunotherapy designed to target ...
China’s National Intellectual Property Administration has issued notification to grant patent to PolTREG Chinese patent covers intrathecal ...