GlobalData’s report assesses the drugs in the Histamine H4 Receptor pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline.

These factors can activate mast cells to release proinflammatory mediators and some of them, for example, histamine, tryptase and nerve growth factor, can stimulate sensory C-fibers. Since ...

Mast cells are cells of the immune system which are found around blood vessels in the skin, gastrointestinal tract, respiratory tract, and genitourinary tract. They contain granules of several ...

"It was super disappointing and depressing to watch everyone else living their lives," Cray told Newsweek about her diagnosis.

High histamine foods include fermented foods, alcohol, processed meats, aged cheeses, and more. Histamine is a chemical in the body typically associated with causing allergic reactions to substances ...

Low-dose aspirin is helpful in some patients, because it causes continuous degranulation and prevents extreme peaks of histamine release from mast cells. Doses of 40 mg per day have been used ...

lumc.nl Objective Mast cells may play a role in rheumatoid arthritis (RA), but activation of human mast cells in autoimmune settings has been little studied. Toll-like receptors (TLR) and Fcγ ...

This transport is essential both for sustaining synaptic transmission and for limiting the toxic effects of monoamines. Here, synthesis of the monoamine histamine by histidine decarboxylase (HDC) and ...