Innovative research has provided compelling evidence that perceived stress can directly trigger the relapse of psoriatic skin ...

Mast cells participate in all the stages of acute inflammatory responses ... One study showed that the MC stabilizer disodium cromoglycate inhibited MC degranulation without affecting IL-10 production ...

particularly through mast cell degranulation," explains Professor Amos Gilhar, lead researcher from the Skin Research ...

The lesions in TMEP are not pruritic and do not produce Darier's sign because mast cell proliferation may not be sufficient to produce significant degranulation (Alto & Clarcq, 1999; Hogan & Lewis ...

Amsterdam, Netherlands) Innovative research has provided compelling evidence that perceived stress can directly trigger ...

particularly through mast cell degranulation," explains Professor Amos Gilhar, lead researcher of the study. "This is further amplified by corticotropin-releasing hormone (CRH) and NGF, which heighten ...

A standard treatment for mastocytosis is difficult to apply to individual patients based on the variable clinical course. A general consensus for using antimediator agents such as antihistamines ...

umin.ac.jp Objective Extracellular ATP mediates mast cell-dependent intestinal inflammation via P2X7 purinoceptors. We have previously shown that CD300f (also called the leucocyte ...

lumc.nl Objective Mast cells may play a role in rheumatoid arthritis (RA), but activation of human mast cells in autoimmune settings has been little studied. Toll-like receptors (TLR) and Fcγ ...

MRGPRX2 is most abundantly found on mast cells and peripheral sensory neurons. MRGPRX2 can trigger IgE-independent activation (degranulation) via multiple ligands, which can lead to a variety of ...