Indolent systemic mastocytosis has skin involvement in almost all cases. Mast cell infiltrates may be detected in various organ systems, including the liver, spleen, or GI tract. The bone marrow ...

The case of a 70-year-old woman with systemic mastocytosis (SM) who demonstrated cutaneous, bone marrow, and gastrointestinal involvement was presented at the 12th annual meeting of the Society of ...

A local increase of heparin in the bone marrow would not necessarily be reflected by systemic effects of heparin excess. Perhaps only a minor increase is necessary for a local action at the ...

Cogent Biosciences' uncertain competitive edge may compel investors to sit on the sidelines. Read more about the cautious ...

A new analysis of data from the PATHFINDER study confirms that avapritinib offers efficacy and a favorable risk-benefit profile for patients with advanced systemic mastocytosis (AdvSM ... Furthermore, ...

Bone marrow is a spongy organ that fills the center of various bones of your body. It is where stem cells produce red and white blood cells and platelets. Without bone marrow, you couldn't move oxygen ...

What Are Blood and Bone Marrow Cancers? Bone marrow cancer is a form of cancer that starts in the spongy tissue -- the marrow -- inside your bones. Marrow’s main job is to make blood cells.

Mastocytosis can be difficult to diagnose and it can a very frustrating process. Correctly identifying the clinical symptoms aids in the diagnosis. Sometimes skin lesions and bone marrow are biopsied ...

Sudipto Mukherjee, MD, PhD, MPH, of Cleveland Clinic, describes the steps clinicians should take when they encounter clinical abnormalities that may point to systemic mastocytosis. (1:48 ...

The following is a summary of “Comparison of prognostic scores according to WHO classification in 170 patients with advanced mastocytosis and C-finding treated with midostaurin,” published in the ...

Bone marrow is a soft, spongy material inside your bones where blood cells are made. These blood cells are important for a healthy immune system. (Photo Credit: Wendy Hiller Gee/Eric Olson/WebMD ...

Here’s what else the team learned. In Systemic Mastocytosis, What’s the Impact of Type I Interferon Autoantibodies? Investigators from the National Institutes of Health recently tackled the ...