Schematic representation of MAVS gene. Ribosome recognition sites for translation are located at position 1 and position 142 on the MAVS gene, highlighted by the yellow band.

The discovery and identification of unknown RLR-mediated antiviral innate immune regulatory factors will enrich the knowledge of RLR signaling regulation and further guide antiviral practice. In this ...

Signaling molecule complex formation, such as that involving MAVS, is required for antiviral responses. Other pattern-recognition receptors (PRRs), including Toll-like receptors, NOD-like ...

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Atea Pharmaceuticals’ antiviral has failed another COVID-19 trial, but the biotech still holds out hope the candidate has a future in hepatitis C. The oral nucleotide polymerase inhibitor ...

Figure 1. Signal transduction mechanism of EGFR (epidermal growth factor receptor) transactivation by angiotensin II (AngII) in vascular smooth muscle cells leading to vascular remodeling. Please note ...

Here’s how it works. The best cell phone signal boosters help boost your cell reception in your home, office, or car. If you rely on your wireless service for your home or vehicular internet ...

NEW YORK — Sixteen floors above Central Park, Kris White keeps his gentler pathogens behind an unlocked stainless steel freezer door, in brightly colored boxes caked with frost. There’s an ...

HCV evades host antiviral innate immune responses to mediate a persistent infection in the liver. This review focuses on anti-HCV innate immune sensing, signaling and effectors and the processes ...