For the first time, a molecular mechanism is identified, for experimental acceleration and deceleration (rejuvenation) of sperm epigenetic aging.

NKT2152, a novel HIF2a inhibitor, demonstrates significant efficacy in patients with advanced clear cell renal cell carcinoma ...

Thus, NaCl enhances tumor cell death in vitro and in vivo. Elevated levels of genes like mTOR, tumor necrosis factor (TNF), interleukin-2 (IL-2), programmed cell death 1 (PD-1), mitogen-activated ...

Tumors are one of the most misunderstood diagnoses or conditions. While no one wants to be told they have one, many people don't realize that a tumor is nothing more than a clump of abnormal cells ...

For this study, researchers used both mouse and breast cancer cell models to find out ... pathways such as AMPK and inhibition of downstream mTOR signaling — a ubiquitous kinase enzyme that ...

Sep. 13, 2024 — A drug that delivers chemotherapy directly to tumors has shown impressive activity against some of the hardest-to-reach cancer cells: those that have spread to the brain in ...