Darier's sign is a change observed after stroking lesions on the skin of a person with systemic mastocytosis or urticaria pigmentosa. [1] Stroking the skin leads to a localised subcutaneous ...

UP lesions will urticate when stroked with a blunt object. This is known as Darier's sign and is a diagnostic feature of mastocytosis (Hogan & Lewis, 2002; Kuznar, 1998; Leaf, Jaecks ...

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If you're coping with episodic facial flushing you may be frustrated at how hard it is to get a diagnosis. What is facial flushing related to mastocytosis like and what are some of the conditions ...

Opens in a new tab or window An analysis of registry data concluded that hypersensitivity reactions in patients with mastocytosis are caused by exposure to certain triggers, including low tryptase ...

If you live in the modern age and have access to the Internet, chances are you’re going to have to digitally sign a document at some point or another. You no longer have to laboriously print out ...

Sudipto Mukherjee, MD, PhD, MPH, of Cleveland Clinic, describes the steps clinicians should take when they encounter clinical abnormalities that may point to systemic mastocytosis. (1:48 ...

The following is a summary of “Comparison of prognostic scores according to WHO classification in 170 patients with advanced mastocytosis and C-finding treated with midostaurin,” published in the ...