Damaging LXRα variants are linked to liver cholesterol buildup and hepatitis, emphasizing the receptor's importance in cholesterol sensing and liver function.

Some people who use essential oils claim that they’re helpful for reducing inflammation in the body. Diffusing essential oils or using them in massage may help manage inflammation. You should ...

In the absence of inflammation, HDL has a complement of antioxidant ... or statins Decrease coronary stenosis and clinical events LXR agonists (GW3965, GlaxoSmithKline, Philadelphia, PA) In ...

Tuft cells have important roles in type 2 immunity and antimicrobial responses in mucosal tissues. This Review provides an overview of intestinal tuft cells, providing insights into their ...

The past decade has seen significant advances in our understanding of skeletal homeostasis and the mechanisms that mediate the loss of bone integrity in disease. Recent breakthroughs have arisen ...

The proposed mechanisms of action of some of the nutraceutical supplements on the mammalian cholesterol pathway are shown in Figure 2. Virtually all studies have shown very high safety profiles ...