Mannose receptor - Wikipedia
网页The mannose receptor (Cluster of Differentiation 206, CD206) is a C-type lectin primarily present on the surface of macrophages, immature dendritic cells and liver sinusoidal endothelial cells, but is also expressed on the surface of skin cells such as human dermal fibroblasts and keratinocytes.
The M2 macrophage marker CD206: a novel prognostic indicator for acute ...
网页2019年11月3日 · CD206, also known as mannose receptor C type 1 (MRC1), is a cell-surface protein abundantly presents on selected populations of macrophages and dendritic cells. 16 As for macrophages, CD206 is normally expressed on the M2 but not M1 subtype and therefore serves as a useful marker to identify the M2 phenotype.
人免疫细胞标志物指南 | Cell Signaling Technology
网页相反，m2-样巨噬细胞可通过 cd163 或 cd206 表达被鉴定出，并且能通过分泌免疫抑制细胞因子（例如 il-10）以及促进 th2 反应来促进肿瘤生长。 M2 巨噬细胞还表达免疫抑制酶精氨酸酶，这种精氨酸酶会耗竭肿瘤微环境中的精氨酸，从而导致 T 细胞增殖和功能减弱。
CD206 + M2-like macrophages regulate systemic glucose
网页2017年8月18日 · We show that adipose tissue CD206 + cells are primarily M2-like macrophages, and ablation of CD206 + M2-like macrophages improves systemic insulin sensitivity, which was associated with an ...
Macrophage Mannose Receptor CD206 Predicts Prognosis in
网页2019年12月10日 · CD206, a mannose receptor, is mainly expressed on the surface of alternatively activated macrophages where it acts as a pattern recognition receptor and plays a role in innate and...
CD206 - National Center for Biotechnology Information
网页2019年10月10日 · CD206 is a C-type lectin, alternatively termed as the macrophage mannose receptor, that is, generally expressed by tissue macrophages, dendritic cells, and specific lymphatic or endothelial cells. CD206 plays an important role in immune homeostasis, but its high expression has been increasingly detected in the tumor microenvironment 33 .
The Mannose Receptor: From Endocytic Receptor and Biomarker …
网页The mannose receptor (MR), also termed CD206, is a member of the C-type lectin (CLEC) family. Members of this family contain C-type lectin domains (CTLDs), which play an important function in ligand recognition.
Macrophage mannose receptor, CD206, predict prognosis in
网页2018年9月3日 · CD206, known as mannose receptor and C-type lectin, is primary expressed on the surface of macrophages and immature dendritic cells, where it acts as a pattern recognition receptor (PRR)...
The M2 macrophage marker CD206: a novel prognostic indicator …
网页2019年11月3日 · When analyzed in a meta-analysis, CD206 as a continuous variable showed superior predictive performance than classical prognosticators in AML (BAALC, ERG, EVI1, MN1, and WT1). In summary, M2 macrophages are preferentially enriched in AML. The M2 marker CD206 may serve as a new prognostic marker in AML.
Macrophage Activation Markers, CD163 and CD206, in Acute-on …
网页2020年5月9日 · Soluble CD163 and CD206 are promising biomarkers to reveal and quantify activation of the resident liver macrophages (Kupffer cells) [6], which have gained attention from a clinical perspective especially during the last decade. New aspects of immunopathology in ACLF are highly relevant to support and extent current understandings.
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