Vaping-Related Acute Parenchymal Lung Injury - CHEST
网页2020年5月19日 · In this review, we detail the clinical, radiographic, and pathologic patterns of lung injury that are attributable to vaping and provide an overview of the scientific literature to date on the effects of vaping on respiratory health.
Acute and chronic effects of vaping electronic devices on lung ...
网页Here we review the latest studies on the impact of short and long term e-cigarette aerosol inhalation on molecular pathways, cellular recruitment, gas exchange and airway physiology. Inflammatory cytokines IL-6 and IL-8 were increased by e-cigarette exposures, and a variety of immune cells were recruited to the parenchyma and airways across models.
Multidimensional assessment of the biological effects of electronic ...
网页2024年2月23日 · Cigarette smoke (CS) exposure is known to cause injury to respiratory tract epithelial cells and is a contributing factor in the development of chronic obstructive pulmonary disease and lung...
Vaping and Lung Inflammation and Injury - PMC - National …
网页2022年2月2日 · Overall, exposure to e-cigarettes induces secretion of proinflammatory cytokines, including interleukin (IL)-1β, IL-6, IL-8, and tumor necrosis factor alpha (TNF-α), from epithelial cells and immune cells in the upper airway and lung (80, 92–96). A particular pattern of neutrophil signals has been detected across studies.
What are the mechanisms underlying vaping-induced lung injury?
网页2020年5月5日 · The exact mechanism behind the lung injuries seen in EVALI is unknown, but we propose two possibilities (Figure 1A): (a) a chemical inhaled within the aerosol created by vaping or dabbing is directly cytotoxic to certain lung cells, leading to cellular necrosis, neutrophilic inflammation, and collateral damage, or, alternatively, (b) a two-hit ...
What are the mechanisms underlying vaping-induced lung injury…
网页2020年5月11日 · The exact mechanism behind the lung injuries seen in EVALI is unknown, but we propose two possibilities (Figure 1A): (a) a chemical inhaled within the aerosol created by vaping or dabbing is directly cytotoxic to certain lung cells, leading to cellular necrosis, neutrophilic inflammation, and collateral damage, or, alternatively, (b) a two-hit p...
Impact of vaping on respiratory health - The BMJ
网页2022年7月18日 · We review the clinical manifestations of vaping related lung injury, including the EVALI outbreak, as well as the effects of chronic vaping on respiratory health and covid-19 outcomes. We conclude that vaping is not without risk, and that further investigation is required to establish clear public policy guidance and …
Cardiopulmonary Impact of Electronic Cigarettes and Vaping …
网页2023年7月17日 · The outbreak of e-cigarette or vaping product use–associated lung injury in the United States in 2019, which led to >2800 hospitalizations, highlighted the risks of e-cigarettes and vaping products.
Understanding potential mechanisms of harm: the drivers of …
网页2021年8月10日 · In a range of studies examining cytokine secretion from both THP-1 cell lines and bronchoalveolar lavage (BAL)-derived macrophages, proinflammatory cytokines, most notably the robust recruiter of neutrophils IL-8, are upregulated in response to e-cigarette vapor condensate, extract, and supplemented media treatments (36, 37, 42).
VpALI—Vaping-related Acute Lung Injury: A New Killer Around …
网页2019年11月22日 · Recently, a multistate epidemic has emerged surrounding vaping-related acute lung injury, prompting the Centers for Disease Control and Prevention to list an official health advisory. In this review, we describe the current literature on the epidemiology, clinical significance, as well as recommended evaluation and treatment of vaping-related ...