CD34 - Wikipedia
网页CD34 is a transmembrane phosphoglycoprotein protein encoded by the CD34 gene in humans, mice, rats and other species. [5] [6] [7] CD34 derives its name from the cluster of differentiation protocol that identifies cell surface antigens.
CD34—Structure, Functions and Relationship with Cancer Stem Cells
网页2023年5月12日 · CD34 is primarily known as a biomarker for hematopoietic stem cells (HSCs) and hematopoietic stem precursor cells, but it has also been identified as a marker for several non-hematopoietic cells.
Concise Review: Evidence for CD34 as a Common Marker for …
网页2014年5月23日 · CD34 is a transmembrane phosphoglycoprotein, first identified on hematopoietic stem and progenitor cells. Clinically, it is associated with the selection and enrichment of hematopoietic stem cells for bone marrow transplants.
CD34 - an overview | ScienceDirect Topics
网页CD34 is a transmembrane glycoprotein that is expressed on early lymphohematopoietic stem cells, progenitor cells, endothelial cells, embryonic fibroblasts, and some cells in fetal and adult nervous tissue. It is also expressed on pluripotent and committed stem cells in colony-forming assays.
Who is hematopoietic stem cell: CD34+ or CD34-? - PubMed
网页CD34 is a marker of human HSC, and all colony-forming activity of human bone marrow (BM) cells is found in the CD34+ fraction. Clinical transplantation studies that used enriched CD34+ BM cells indicated the presence of HSC with long-term BM reconstitutional ability within this fraction.
CD34 Gene - GeneCards | CD34 Protein | CD34 Antibody
网页2024年8月5日 · CD34 (CD34 Molecule) is a Protein Coding gene. Diseases associated with CD34 include Dermatofibrosarcoma Protuberans and Sialadenitis. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and …
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网页CD34 - 110kDa glycosylated transmembrane protein; it is a marker of vascular endothelial cells and a sensitive but not specific marker for neoangiogenesis
Not just a marker: CD34 on human hematopoietic stem/progenitor cells ...
网页2017年12月26日 · CD34 is routinely used to identify and isolate human hematopoietic stem/progenitor cells (HSPCs) for use clinically in bone marrow transplantation, but its function on these cells remains elusive. Glycoprotein ligands on HSPCs help guide their migration to specialized microvascular beds in the bone marrow that express vascular …
A sticky wicket: Defining molecular functions for CD34 in hematopoietic …
网页While CD34 expression has been widely exploited for progenitor cell enrichment, very little is known about how CD34 regulates cell behaviour. In this review, we focus on the role of CD34 in hematopoietic stem and progenitor cell (HSPC) function.
CD34 Protein: Its expression and function in inflammation
网页2023年7月14日 · This review recaptures CD34 structure, evolutionary conservation, proposed functions, and role in lung inflammation, to describe current research findings and to provide guidance for future studies on CD34.