Effect of Berberine on Hyperuricemia and Kidney Injury: A …
网页2021年7月27日 · BBR exerts anti-HUA and nephroprotective effects via inhibiting activation of NLRP3 inflammasome and correcting the aberrant expression of URAT1 in kidney. BBR might be a novel therapeutic agent for treating HUA. Keywords: berberine, hyperuricemia, URAT1, NLRP3 signaling pathway. Go to:
Berberine ameliorates chronic kidney disease through inhibiting …
网页2023年4月1日 · This study showed that berberine, a natural drug with low oral availability, significantly ameliorated chronic kidney disease by altering the composition of the gut microbiota and inhibiting the production of gut-derived uremic toxins, including p-cresol.
Protective effects of berberine on various kidney diseases: …
网页2022年10月1日 · Several scholars have found that BBR has promising renoprotective effects against a wide range of renal illnesses, including diabetic nephropathy, renal aging, renal fibrosis, chemotherapy-induced nephrotoxicity, heavy metal-induced nephrotoxicity, aminoglycoside-induced nephrotoxicity, renal stones, and others, implying that BBR has an ...
Advances of berberine against metabolic syndrome-associated kidney …
网页2023年2月6日 · The mechanisms of BBR in hyperuricemia and related kidney disease are listed below. First, BBR lowers UA by inhibiting UA biosynthesis and promoting UA excretion. BBR suppresses the expression of xanthine oxidase (XOD), urate transporter 1 (URAT1), and glucose transporter 9 (GLUT9) to lower UA (Shan et al., 2022).
Protective effects of berberine on various kidney diseases
网页2022年10月1日 · Several scholars have found that BBR has promising renoprotective effects against different renal illnesses, including diabetic nephropathy, renal fibrosis, renal ischemia, renal aging, and renal stones.
Berberine Benefit CKD | Chronic Kidney Disease Healthcare
网页2024年5月26日 · Mechanism of Action. Berberine exerts its effects through multiple mechanisms. It activates AMP-activated protein kinase (AMPK), which plays a crucial role in regulating metabolism. AMPK activation improves insulin sensitivity, reduces inflammation, and mitigates oxidative stress.
Effect of Berberine on Hyperuricemia and Kidney Injury: A …
网页2021年7月27日 · BBR exerts anti-HUA and nephroprotective effects via inhibiting activation of NLRP3 inflammasome and correcting the aberrant expression of URAT1 in kidney. BBR might be a novel therapeutic agent for treating HUA.
Berberine protects against diabetic kidney disease via ... - PubMed
网页Restoration of PGC-1α activity and the energy homeostasis by berberine might be a potential therapeutic strategy against DKD. PGC-1α-mediated mitochondrial bioenergetics could play a key role in lipid disorder-induced podocyte …
Protective effects of berberine on various kidney diseases: …
网页2022年10月1日 · Several scholars have found that BBR has promising renoprotective effects against different renal illnesses, including diabetic nephropathy, renal fibrosis, renal ischemia, renal aging, and renal stones.
Berberine ameliorates renal interstitial inflammation and fibrosis …
网页2023年10月9日 · Berberine acts via multiple pathways to alleviate fibrosis in various tissues and shows renoprotective effects. However, its role and underlying mechanisms in renal fibrosis remain unclear. Herein, we aimed to investigate the protective effects and molecular mechanisms of berberine against unilateral ureteric obstruction-induced renal fibrosis.
跳至内容