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  1. AAV Serotypes Eleven serotypes of AAV have thus far been identified, with the best characterized and most commonly used being AAV2. These serotypes differ in their tropism, or the types of cells they infect, making AAV a very useful system for preferentially transducing specific cell types.
    CNS: AAV1, AAV2, AAV4, AAV5, AAV8, AAV9
    Heart: AAV1, AAV8, AAV9
    Kidney: AAV2
    Liver: AAV7, AAV8, AAV9

    Adeno-associated Virus (AAV) Guide - Addgene

    www.addgene.org/guides/aav/
    www.addgene.org/guides/aav/
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    How many serotypes of AAV are there?
    Eleven serotypes of AAV have thus far been identified, with the best characterized and most commonly used being AAV2. These serotypes differ in their tropism, or the types of cells they infect, making AAV a very useful system for preferentially transducing specific cell types.

    Adeno-associated Virus (AAV) Guide - Addgene

    addgene.org
    Do adeno-associated virus serotypes interact with the cellular AAV receptor?
    Pillay, S. et al. Adeno-associated virus (AAV) serotypes have distinctive interactions with domains of the cellular AAV receptor. J. Virol. 91, e00391-17 (2017). Summerford, C., Johnson, J. S. & Samulski, R. J. AAVR: a multi-serotype receptor for AAV. Mol. Ther. 24, 663–666 (2016).

    Adeno-associated virus vector as a platform for gene therapy delivery

    nature.com
    What is the serotype of aav3?
    The third serotype of AAV (AAV3) was originally isolated from humans [34, 45]. Similar to AAV2, this serotype uses HSPG, FGFR1, and LR receptors [60, 74], along with the human HGFR (hHGFR) receptor . Iodixanol gradient ultracentrifugation along with ion exchange chromatography have been used for AAV3 purification .

    Various AAV Serotypes and Their Applications in Gene Therapy: An

    ncbi.nlm.nih.gov
    Do adeno-associated virus (AAV) peptides enhance the transduction of serotype 9?
    Saraiva J, Nobre RJ, Pereira de Almeida L. Gene therapy for the CNS using AAVs: the impact of systemic delivery by AAV9. J Control Release. 2016;241:94–109. Meng Y, Sun D, Qin Y, Dong X, Luo G, Liu Y. Cell-penetrating peptides enhance the transduction of adeno-associated virus serotype 9 in the central nervous system.

    Changing trends in the development of AAV-based gene therapies ... - …

    nature.com
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  3. PubMed
    https://pubmed.ncbi.nlm.nih.gov/36899921翻译

    Various AAV Serotypes and Their Applications in Gene Therapy: An ...

  4. Addgene
    https://www.addgene.org/guide…翻译

    Adeno-associated Virus (AAV) Guide - Addgene

    网页Learn about the 11 serotypes of AAV and how they differ in their ability to infect various tissues and cells. Find out how to use pseudotyping to …

    • CNS: AAV1, AAV2, AAV4, AAV5, AAV8, AAV9
    • Kidney: AAV2
    • Heart: AAV1, AAV8, AAV9
    • Liver: AAV7, AAV8, AAV9

  5. AAV Serotype的图片

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    gigaviralvectors.uliege.be
    About the virus vectors
    medscape.org
    Exploring the Use of Adeno-Associated Virus for Gene Therapy (Transcript)
    cell.com
    Adeno-associated Virus Serotypes: Vector Toolkit for Human Gene Therapy: Molecular Therapy
    vnl.princeton.edu
    Types of Viruses | PNI Viral Core Facility
    gigaviralvectors.uliege.be
    About the virus vectors
    www1.biocat.com
    Adeno-associated Virus Technology
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  6. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000783翻译

    Various AAV Serotypes and Their Applications in Gene Therapy: An ...

  7. PubMed
    https://pubmed.ncbi.nlm.nih.gov/28679762翻译

    Adeno-associated Virus (AAV) Serotypes Have Distinctive

  8. Nature
    https://www.nature.com/articles/s41392-024-01780-w翻译

    Adeno-associated virus as a delivery vector for gene therapy of …

  9. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571256翻译

    Adeno-associated Virus (AAV) Serotypes Have Distinctive …

  10. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310307翻译

    Adeno-Associated Virus (AAV) Gene Delivery: Dissecting Molecular ...

  11. Nature
    https://www.nature.com/articles/s41434-022-00363-0翻译

    Changing trends in the development of AAV-based gene therapies …

  12. Nature
    https://www.nature.com/articles/s41573-019-0012-9翻译

    Adeno-associated virus vector as a platform for gene therapy

  13. PubMed
    https://pubmed.ncbi.nlm.nih.gov/16824801翻译

    Adeno-associated virus serotypes: vector toolkit for human