Biological properties and clinical applications of berberine
网页Berberine, an isoquinoline alkaloid isolated from the Chinese herb Coptis chinensis and other Berberis plants, has a wide range of pharmacological properties. Berberine can be used to treat many diseases, such as cancer and digestive, metabolic, cardiovascular, and neurological diseases.
The clinical efficacy and safety of berberine in the treatment of …
网页2024年3月1日 · Non-alcoholic fatty liver disease (NAFLD) is becoming increasingly prevalent worldwide, emerging as a significant health issue on a global scale. Berberine exhibits potential for treating NAFLD, but clinical evidence remains inconclusive. This meta-analysis was conducted to assess the efficacy and safety of berberine for treating NAFLD.
Biological Activity of Berberine—A Summary Update - PMC
网页2020年11月12日 · Berberine is a plant metabolite belonging to the group of isoquinoline alkaloids with strong biological and pharmacological activity. Currently, berberine is receiving considerable interest due to its anticancer activity based on many biochemical pathways, especially its proapoptotic and anti-inflammatory activity.
The status of and trends in the pharmacology of berberine: a ...
网页2020年1月20日 · 40 Citations. 18 Altmetric. Metrics. Abstract. Berberine has significant antibacterial and antipyretic effects and is a commonly used drug for treating infectious diarrhoea. The current research data show that the pharmacological effects of berberine are numerous and complex, and researchers have been enthusiastic about this field.
Frontiers | Berberine: A Review of its Pharmacokinetics Properties …
网页2021年11月2日 · Berberine, a naturally occurring isoquinoline alkaloid form Rhizoma coptidis, is widely used in China as a folk medicine for its antibacterial and anti-inflammatory properties. Promisingly, an increasing number of studies have identified several cellular and molecular targets for berberine, indicating its potential as an alternative therapeutic ...
The effect of Berberine on weight loss in order to prevent
网页This study provides a critical overview of experimental studies in vitro, in humans, and in animals that evaluated the efficacy of Berberine and its effect on management of obesity and the related metabolic consequences. As a result of this review, we summarized the effects of Berberine in different …
Berberine: Botanical Occurrence, Traditional Uses, Extraction …
网页2018年8月21日 · Berberine, a quaternary protoberberine alkaloid (QPA) is one of the most widely distributed alkaloid of its class. Current studies suggest that isolation of the QPA alkaloids from their matrix can be performed using several methods.
Berberine in the Treatment of Diabetes Mellitus: A Review
网页Berberine is an alkaloid found in plants. It has neuroprotective, anti-inflammatory and hypolipidemic activities. The research proves that it also strongly impacts carbohydrate metabolism. The compound also protects pancreatic β-cells and increases sensitivity to insulin in peripheral tissues via th ….
De novo biosynthesis of berberine and halogenated ... - Nature
网页2023年2月9日 · Berberine is a plant-derived benzylisoquinoline alkaloid (BIA) with multiple pharmaceutical activities. It exerts wide-spectrum antimicrobial and antiviral effects against pathogenic bacteria...
Effects and mechanisms of berberine in diabetes treatment
网页2012年8月1日 · Berberine was shown to decrease blood glucose, enhance insulin sensitivity and reduce weight gain in both dietary and genetic rodent models of type 2 diabetes. In high-fat diet induced obese rats, berberine decreased FBG, PBG, fasting insulin, homeostasis model of assessment-insulin resistance (HOMA-IR) and body weight 4, 7, 8.