Efficacy of Berberine Alone and in Combination for the Treatment …
网页2017年1月16日 · The combination of Preparation plus berberine was found to be superior to berberine alone in terms of effect on LDL, TC, and TG (P < .000). The authors found no effect on their specified safety variables (β-glucuronidase, glutamate oxaloacetate transaminase, glutamate pyruvate transaminase, and creatinine phosphokinase) in …
Overall and Sex-Specific Effect of Berberine for the Treatment of ...
网页2023年3月21日 · We found that on average berberine can modestly reduce low-density lipoprotein (LDL) cholesterol by 0.5 mmol/L (18 mg/dL) and triglycerides by 0.3 mmol/L (30 mg/dL). Berberine also increases high-density lipoprotein (HDL) …
Can Berberine Lower Your Lipid Levels? - Verywell Health
网页2021年7月21日 · It is thought that berberine has the ability to increase the number of LDL receptors in the liver, which may help increase the clearance of LDL cholesterol from the body. Berberine also appears to act on signaling …
Efficacy and Safety of Berberine Alone for Several Metabolic …
网页2021年4月26日 · Conclusion: Berberine can improve obesity and hyperlipidemia by reducing TG, TC, and LDL and increasing HDL; reduce insulin resistance to improve type Ⅱ diabetes; and prevent diabetic encephalopathy. Keywords: meta-analysis, systematic review, metabolic diseases, randomized clinical trials, berberine. Go to: Introduction.
Efficacy and Safety of Berberine Alone or Combined with Statins …
网页To systematically evaluate the efficacy and safety of berberine for the treatment of hyperlipidemia, six electronic literature databases including SinoMed, CNKI, WanFang Data, PubMed, Embase and The Cochrane Library were searched to collect clinical randomized controlled trials (RCTs) of berberine a ….
Efficacy and safety of berberine for dyslipidaemias: A systematic ...
网页2018年11月15日 · Meta-analysis showed that berberine significantly reduced levels of total cholesterol (TC) (MD = -0.47 mmol/l 95% CI [-0.64, -0.31], p < 0.00001), low-density lipoprotein cholesterol (LDL-C) (MD =-0.38 mmol/l 95% CI [-0.53, -0.22], p < 0.00001) and triglycerides (TG) (MD = -0.28 mmol/l 95% CI [-0.46, -0.10], p = 0.002).
Efficacy and underlying mechanisms of berberine against lipid …
网页2023年11月15日 · BBR can directly upregulate LDLR mRNA expression in hepatocytes by activating the Jun N-terminal kinase (JNK)/c-Jun signaling pathway (Fan et al., 2021), resulting in increased LDL uptake, lower circulating LDL-C levels, and alleviation of AS. These studies suggest that BBR plays a role in reducing circulating cholesterol levels …
Efficacy and safety of berberine for dyslipidemia: study protocol …
网页2021年1月22日 · The therapeutic dose of BBR (0.5 g) is generally safe and well-tolerated, and gastrointestinal reactions are most often caused by overdose (≥ 4 g). A recent systematic review and meta-analysis demonstrated that BBR could significantly reduce the levels of TC, LDL-C, and TG in patients with dyslipidemia [13].
Cholesterol-lowering supplements may be helpful - Mayo Clinic
网页2022年11月10日 · Berberine. May reduce low-density lipoprotein (LDL, or "bad") cholesterol and triglycerides. May cause diarrhea, constipation, gas, nausea or vomiting; may cause harm to babies during pregnancy and breastfeeding. Fish oil. May reduce triglycerides.
Berberine: Benefits, supplements, side effects, dosage, and more
网页2023年10月20日 · It may help reduce LDL, or “bad” cholesterol, and increase high-density lipoprotein, or “good” cholesterol. A literature review found that berberine combined with lifestyle changes works ...