Medication-induced hair loss: An update - Journal of the …
网页This article discusses drug-induced hair loss, which can occur with many drugs including cytotoxic agents, biologics, and immunomodulating agents, among others. It outlines the diagnosis and management of drug-induced alopecia, with a …
Nanostructured lipid carriers promote percutaneous absorption …
网页2024年8月1日 · Topical application of TFB nanoparticles prevents the onset of alopecia areata in C3H mice model. (a) The treatment schedule for the prevention test of imiquimod-induced alopecia areata in C3H mouse. (b) Representative images of hair changes in model mice after treatment. Red box represents the …
网页ALOPECIA AREATA Drug-induced alopecia areata (AA) is rare but can be caused by monoclonal antibodies targeting cyto-kines, such as tumor necrosis factor-alpha and inter-leukin4(eg,infliximabanddupilumab,respectively), as well as immune checkpoint inhibitors.77 Their blockade or inhibition of their effects (such as with
Induction of alopecia areata in C3H/HeJ mice using polyinosinic ...
网页2018年8月21日 · We examined histological changes in affected mice to further characterize the IFNγ and poly (I:C)-induced AA in C3H/HeJ mice. Similar to spontaneously developed AA, inflammatory infiltrates ...
Review Mouse Models of Alopecia Areata: C3H/HeJ Mice Versus …
网页2020年11月1日 · Development of alopecia areata is associated with higher central and peripheral hypothalamic-pituitary-adrenal tone in the skin graft induced C3H/HeJ mouse model
Rare Cutaneous Side Effects of Imiquimod: A Review on Its …
网页2023年8月1日 · Although imiquimod is considered to be a safe drug and is generally well tolerated, an increasing number of rare cutaneous side effects, such as vitiligo, pemphigus, psoriasis, and lichen planus, are being reported. Most of these rare cutaneous side effects are reversible, but a few are irreversible or even fatal.
Immune modulation of hair follicle regeneration | npj ... - Nature
网页2020年5月11日 · The collapse of these immunoinhibitory mechanisms is implicated in the development of immune-mediated alopecias including primary cicatricial alopecias (PCAs) and alopecia areata (AA) 35,37....
网页2.12 Since alopecia areata is proposed to be mediated through T H 2 immunity, imiquimod has been considered as a possible agent for treatment. In a case series by Sommerfeld and Poppova,13 partial or total hair regrowth was observed in 5 patients with alopecia areata after topical applica-tion of imiquimod. Poor hair growth was seen in a
Imiquimod-enhanced immunotherapy with diphencyprone for
网页Imiquimod-enhanced immunotherapy with diphencyprone for patients with alopecia areata. Abstract. Topical immunotherapy with dyphencyprone (DPCP) is widely used in patients with alopecia areata (AA). It can produce a contact dermatitis that is believed to decrease Th1 response, predominant in AA.
Mouse Models of Alopecia Areata: C3H/HeJ Mice Versus the
网页The C3H/HeJ model has long dominated basic alopecia areata (AA) in vivo research and has been used as proof-of-principle that Jak inhibitors are suitable agents for AA management in vivo.