Proflavine - Wikipedia
网页Proflavine, also called proflavin and diaminoacridine, is an acriflavine derivative, a disinfectant bacteriostatic against many gram-positive bacteria. [1] It has been used in the form of the dihydrochloride and hemisulfate salts as a topical antiseptic, and was formerly used as a urinary antiseptic. Proflavine is also known to have a mutagenic ...
Proflavine: Uses, Interactions, Mechanism of Action - DrugBank …
网页2005年6月13日 · Proflavine is an acriflavine derivative which is a disinfectant bacteriostatic against many gram-positive bacteria. Proflavine is toxic and carcinogenic in mammals and so it is used only as a surface disinfectant or for treating superficial wounds.
Proflavine | C13H11N3 | CID 7099 - PubChem
网页Proflavine Hemisulfate is the hemisulfate salt form of proflavine, an acridine-derived fluorescent contrast and disinfectant agent that can potentially be used for cellular imaging and antiseptic purposes.
Proflavine (3,6-Diaminoacridine) | 抗菌剂 | MCE - MCE-生物活性 ...
网页Proflavine, an acridine dye, is a known DNA intercalating agent. Anti-microbial agent. Proflavine behaves as a pore blocker for K ir 3.2. Proflavine is a potential lead compound for K ir 3.2-associated neurological diseases.
2. Biological Actions of Methylene Blue and Proflavine and Methods
网页2020年4月15日 · Also known as a biologic dye, proflavine (PRO) is an acriflavine derivative, used as a disinfectant and bacteriostatic agent against many gram-positive bacteria as well as a urinary antiseptic.
Proflavine an acridine DNA intercalating agent and strong …
网页2017年12月1日 · Proflavine, an acridine dye is a known DNA intercalating agent. Proflavine, an acridine dye with a flavine nucleus can penetrate the epidermal and dermal structures in the in vivo stained cells and accumulate in the cell nuclei, only cells of the central nervous system did not absorb any proflavine [1].
Proflavine - an overview | ScienceDirect Topics
网页Proflavine is a brightly coloured acridine derivative that was extensively used during the Second World War in the treatment of wounds. 15 Modern use is as a prophylactic agent in surgical wounds packed with gauze soaked in proflavine hemisulfate solution. It is an intercalating agent that inhibits bacteria by binding to DNA and prevents ...
Proflavine - American Chemical Society
网页2005年9月5日 · Proflavine is a synthetic acridine dye that was used as a powerful antiseptic during World War II to dress wounds. In recent years it has been studied extensively in novel RNA-targeted antiviral drugs and as …
Photo-activated proflavine degrades protein and impairs enzyme …
网页2021年12月21日 · Proflavine and its acridine derivatives are shown to infiltrate cells and attach to protein/enzyme and DNA, causing physiological dysfunction and cell death [ 39, 40 ]. When exposed to visible light, proflavine releases a variety of reactive oxygen species, which cause double-stranded breaks in DNA [ 6, 14 ].
Proflavine/acriflavine derivatives with versatile biological activities
网页Proflavine derivatives are extremely interesting chemotherapeutic agents, which have shown promising pharmaceutical potential due to their wide range of biological activities. This review summarizes the current state of research into the anticancer, antimicrobial, antimalarial and antileishmanial pr ….